Asian Americans and prostate cancer: A nationwide population-based analysis

Introduction It remains largely unknown if there are racial disparities in outcomes of prostate cancer (PCa) for Asian American and Pacific Islanders (PIs) (AAPIs). We examined differences in diagnosis, management, and survival of AAPI ethnic groups, relative to their non-Hispanic White (NHW) counterparts.Results Relative to NHWs, Asian Indian/Pakistani, Filipino, Hawaiian, and PI men had significantly worse outcomes. Filipino (odds ratio [OR] = 1.38, 95% CI: 1.27-1.51), Hawaiian, (OR = 1.70, 95% CI: 1.41-2.04), Asian Indian/Pakistani (OR = 1.37, 95% CI: 1.15-1.64), and PI men (OR = 1.90, 95% CI: 1.46-2.49) were more likely to present with metastatic PCa (PConclusions Compared with NHWs, AAPI groups were more likely to present with advanced PCa but had better cancer-specific survival. Conversely, Hawaiian and PI men were at greater risk for PCa-specific mortality. Given the different cancer profiles, our results show that there is a need for disaggregation of AAPI data.@@@@Highlights oSEER data between 1988 and 2010 from patients with prostate cancer were extracted and stratified by ethic groups.oMost Asian Americans/Pacific Islanders groups had lower rates of prostate cancer death except for Hawaiian and Pacific Islanders.oCompared with non-Hispanic Whites, Asian Americans/Pacific Islanders were more likely to present advanced prostate cancer.oThese groups showed a better cancer-specific survival.